In vitro antiplasmodial activity of phospholipases A2 and a phospholipase homologue isolated from the venom of the snake Bothrops asper
Fecha
2012
Autores
Quintana Castillo, Juan Carlos
Vargas L.J.
Segura C.
Gutiérrez J.M.
Pérez J.C.A.
Título de la revista
ISSN de la revista
Título del volumen
Editor
MDPI AG
Resumen
Palabras clave
phospholipase , phospholipase A2 , snake venom , acute toxicity , amino acid sequence , antimalarial activity , antiplasmodial activity , article , bothrops asper , cell fractionation , controlled study , cytotoxicity , drug activity , enzyme active site , enzyme activity , hemolysis , IC 50 , in vitro study , ion exchange chromatography , LD 50 , lethality , nonhuman , nucleotide sequence , peripheral blood mononuclear cell , Plasmodium falciparum , sequence alignment , snake , toxicity testing , Amino Acid Sequence , Animals , Antiprotozoal Agents , Bothrops , Cell Survival , Cells , Cultured , Crotalid Venoms , Erythrocytes , Humans , Lethal Dose 50 , Leukocytes , Mononuclear , Mice , Molecular Sequence Data , Phospholipases , Plasmodium falciparum , Sequence Alignment