Study of Colombia North Wiwa El Encanto Amerindians HLA- genes: Pacific Islanders relatedness

Vista sencilla de ítem
dc.creatorArnaiz Villena, Antonio
dc.creatorPalacio Grüber, Jose
dc.creatorJuarez, Ignacio
dc.creatorMuñiz, Ester
dc.creatorHernández Aguirre, Enio Armando
dc.creatorBayona, Brayan
dc.creatorCampos, Cristina
dc.creatorNuñez, Jorge
dc.creatorLopez-Nares, Adrian
dc.creatorMartin-Villa, Manuel
dc.creatorSilvera, Carlos
dc.creator.mailaarnaiz@med.ucm.eses
dc.creator.mailenio.hernandez@campusucc.edu.coes
dc.date.accessioned2018-06-29T22:01:42Z
dc.date.available2018-06-29T22:01:42Z
dc.date.issued2018-07
dc.description.abstractWe have studied Wiwa/Sanja Amerindians HLA-A, -B, -C, -DRB1 and DQB1 allele frequencies and extended haplotypes in 52 unrelated individuals from “El Encanto” town at Guanachaca riverside. High frequency alleles were in general present in other Amerindian populations. Also, three extended haplotypes and eight ones were respectively both “new found” and already described in Amerindians from North, Central and South America, including Lakota-Sioux, Mayas, Teeneks, Quechua and Aymaras. Analyses of HLA-A*24:02 and -C*01:02 Wiwa high frequency alleles suggested a specific relatedness with another Amerindian and Pacific Islander ethnic groups (these two particular alleles bearing in high frequencies); they include New Zealand Maoris, Taiwanese, Japanese, Papua New Guinea, and Samoans among others. This may indicate that selective forces are maintaining these two alleles high frequency within this wide American/Pacific area.es
dc.identifier.bibliographicCitationArnaiz, V. A., Palacio,G. J., Juareza, I., Hernández, E., Muñiz, E., Bayona, B., Campos, C., et al. (2018). Study of Colombia North Wiwa El Encanto Amerindians HLA- genes: Pacific Islanders relatedness. Human Immunology, 79, 530–531es
dc.identifier.urihttp://hdl.handle.net/20.500.12494/4649
dc.orcidhttp://orcid.org/0000-0003-1196-3956es
dc.publisherUniversidad Cooperativa de Colombia, Facultad de Ciencias de la Salud, Medicina, Santa Martaes
dc.publisher.departmentSanta Martaes
dc.publisher.programMedicinaes
dc.relation.isversionofhttps://doi.org/10.1016/j.humimm.2018.04.016es
dc.rights.accessRightsopenAccesses
dc.rights.ccLicencia CC
dc.subjectHLAes
dc.subjectWiwaes
dc.subjectAmerindianses
dc.subjectColombiaes
dc.subjectSouth Americaes
dc.subjectAmerica Peoplinges
dc.subjectPharmacogenomicses
dc.subjectTransplantationes
dc.subjectEpidemiologyes
dc.titleStudy of Colombia North Wiwa El Encanto Amerindians HLA- genes: Pacific Islanders relatednesses
dc.typeArtículo
Archivos
Bloque original
Mostrando1 - 1 de 1
Miniatura
Nombre:
Study_of_Colombia.pdf
Tamaño:
140.22 KB
Formato:
Adobe Portable Document Format
Descripción:
Descargar
Bloque de licencias
Mostrando1 - 1 de 1
Miniatura
Nombre:
license.txt
Tamaño:
4.41 KB
Formato:
Item-specific license agreed upon to submission
Descripción:
Descargar
Colecciones
Medicina