Publicación: Efecto del pH en la resistencia a la tracción de la sutura poliglactina 910 en diferentes tiempos de exposición: estudio in vitro
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The deficiency in the resistance of the suture material leads to a poor adaptation of the surgical flaps, it is important to know that the suture material can be affected by different factors including the pH. The objective was to evaluate the effect of pH on the tensile strength of the 5.0 caliber polyglactin 910ETHICON® suture at different times. Materials and methods: an in vitro experimental study was carried out, with polyethylene 910 ETHICON® 5.0 suture, with a sample of 51 sections of 8 cm. The variables were tensile strength, pH and time. Each section was immersed in different pH (3.0, 5.0, 7.0 and 8.0) and at different times (15min, 2h, 72h and 168h), later they were subjected to a unidirectional tensile force measured in N / cm2 on an IMADA DS2-dynamometer. 50N previously calibrated, as a negative control, three suture stretches without exposure to pH and zero time were used, the data were analyzed by means of central tendency measurements, a multivariate statistical analysis was performed with software R version 3.4.4 with the Profile function Analysis by Group. Results: The resistance of the control group (without applying any variable) was on average 9.2 N / cm2. After 15 minutes of exposure in buffer substances, the tensile strength was on average 8.35 N / cm2 at pH 3, 7.20 N / cm2 at pH 5, 7.67 N / cm2 at pH 7 and 8.17 N / cm2 at pH 8. After 2 hours it had an average of 7.10 N / cm2 at pH 3, 7.06 N / cm2 at pH 5, 6.46 N at pH7 and 5.07 N / cm2 at pH 8. At 72 hours it was 5.67 N / cm2 at pH 3, 6.42 N / cm2 at pH 5, 6.40 N / cm2 at pH 7 and 5.76 N / cm2 at pH 8 and at 168 hours the average resistance was 2.49 N / cm2 at pH 3. 3.96 N / cm2 at pH 5, 4.03 N / cm2 at pH 7 and 3.79 N / cm2 at pH 8. Conclusions: The tensile strength of polyglactin 910 ETHICHON ® 5/0 decreases over time in both acidic and alkaline pHs, being pH 3 at 168 hours the one that generated the greatest loss of resistance with an average of 2.49 N / cm2.