Publicación: Coinfection of Zika with Dengue and Chikungunya virus
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Universidad Cooperativa de Colombia, Facultad de Ciencias de la Salud, Medicina Veterinaría y Zootecnia, Bucaramanga
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The expansion of Zika virus (ZIKV) and its arrival to many tropical and subtropical countries have allowed the existence of coinfections with other arboviruses that cocirculate in these regions. In this study, we describe the distribution of coinfection of ZIKV with other arboviruses, the detection methods used for the identification of these viruses, and the potential implications of these coinfections regarding the prognosis of patients with the associated disease symptoms. ZIKV coinfection is present in nine countries around the world; it is most prevalent in Brazil, followed by Colombia. The principal technique used to identify coinfections is RT-qPCR. Regarding clinical manifestations, no differences have been found between the clinical signs and symptoms presented by monoinfected patients and by coinfected patients. However, relevant research is currently limited, since most pertinent studies are case reports and small-scale cross-sectional studies. Therefore, the impact that coinfections have on either the severity or recovery of the associated disease remains unknown.