Please use this identifier to cite or link to this item: https://repository.ucc.edu.co/handle/20.500.12494/41786
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dc.creatorBermon A.-
dc.creatorUribe-Rodríguez A.F.-
dc.creatorPérez-Rivero P.F.-
dc.creatorPrieto-Merino D.-
dc.creatorCáceres Rivera, Diana Isabel-
dc.creatorGuio E.-
dc.creatorAtkins L.-
dc.creatorHorne R.-
dc.creatorMurray E.-
dc.creatorSerrano Díaz N.C.-
dc.creatorFree C.-
dc.creatorPerel P.-
dc.creatorCasas J.P.-
dc.date.accessioned2021-12-16T22:15:47Z-
dc.date.available2021-12-16T22:15:47Z-
dc.date.issued2019-
dc.identifierhttps://doi.org/10.1590/s0104-07072011000500010-
dc.identifier.issn20446055es
dc.identifier.urihttp://hdl.handle.net/20.500.12494/41786-
dc.description.abstractIntroduction Anti-platelet therapy, angiotensin-converting enzyme inhibitors/angiotensin II receptor blockers, beta-blockers and statins are cost-effective in patients with atherosclerotic cardiovascular diseases (ASCVD) for reducing the risk of ASCVD events. Unfortunately, there is abundant evidence that adherence to these cardiovascular medications is far from ideal. A recent Cochrane review showed a potential beneficial effect of Short Message Service (SMS) interventions on adherence to medication in ASCVD patients. Methods and analysis The txt2heart study is a pragmatic randomised single-blind controlled trial. The objective is to evaluate the efficacy and safety of an intervention with SMS messages delivered by mobile phones to improve adherence to cardiovascular medications in patients with ASCVD. The intervention consists of behavioural techniques delivered via SMS. The primary outcome is change in blood serum low-density lipoprotein cholesterol levels as an indicator of adherence to statins. Secondary outcomes will include systolic blood pressure as an indicator of adherence to blood-lowering therapies and heart rate as an indicator of adherence to beta-blockers, urine levels of 11-dehydrothromboxane B2, self-reported adherence to cardiovascular medications and rates of cardiovascular death or hospitalisation due to cardiovascular disease. Ethics and dissemination The study will be performed in compliance with the protocol, regulatory requirements, Good Clinical Practice and ethical principles of the Declaration of Helsinki. The Ethics Committee of Fundación Cardiovascular de Colombia evaluated and approved the trial. The txt2heart Colombia trial aims to provide robust evidence to evaluate whether SMS messages delivered through mobile telephones change the behaviour of Colombian patients who have suffered a cardiovascular event. Trial results will be presented to the local health authorities, and if the intervention is effective and safe, we hope this strategy will be implemented quickly because of its low cost and wide-reaching impact on the population. Trial registration number NCT03098186. © Author(s) (or their employer(s)) 2019.es
dc.description.provenanceMade available in DSpace on 2021-12-16T22:15:47Z (GMT). No. of bitstreams: 0 Previous issue date: 2019en
dc.format.extent-es
dc.publisherBMJ Publishing Groupes
dc.relation.ispartofBmj Openes
dc.subject11 oxothromboxane B2es
dc.subjectangiotensin receptor antagonistes
dc.subjectatorvastatines
dc.subjectbeta adrenergic receptor blocking agentes
dc.subjectcardiovascular agentes
dc.subjectdipeptidyl carboxypeptidase inhibitores
dc.subjectfluindostatines
dc.subjecthydroxymethylglutaryl coenzyme A reductase inhibitores
dc.subjectpravastatines
dc.subjectrosuvastatines
dc.subjectsimvastatines
dc.subjectadultes
dc.subjectArticlees
dc.subjectbehavior changees
dc.subjectbloodes
dc.subjectcontrolled studyes
dc.subjectcoronary artery atherosclerosises
dc.subjectheart ratees
dc.subjecthumanes
dc.subjectlow density lipoprotein cholesterol leveles
dc.subjectmedication compliancees
dc.subjectpatient compliancees
dc.subjectprogram efficacyes
dc.subjectrandomized controlled triales
dc.subjectsecondary preventiones
dc.subjectself reportes
dc.subjectsingle blind procedurees
dc.subjectsystolic blood pressurees
dc.subjecttext messaginges
dc.titleEvaluation of the efficacy and safety of text messages targeting adherence to cardiovascular medications in secondary prevention: The txt2heart Colombia randomised controlled trial protocoles
dc.typeArtículo-
dc.creator.mailes
dc.identifier.bibliographicCitationBermon A,Uribe AF,Pérez PF,Prieto D,Cáceres DI,Guio E,Atkins L,Horne R,Murray E,Serrano NC,Free C,Perel P,Casas JP. Evaluation of the efficacy and safety of text messages targeting adherence to cardiovascular medications in secondary prevention: The txt2heart Colombia randomised controlled trial protocol. BMJ Open. 2019. 9. (12):028017. .es
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