Please use this identifier to cite or link to this item: https://repository.ucc.edu.co/handle/20.500.12494/41759
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dc.creatorArdila C.M.-
dc.creatorMartelo-Cadavid J.F.-
dc.creatorBoderth Acosta, G.B,-
dc.creatorAriza-Garcés A.A.-
dc.creatorGuzmán I.C.-
dc.date.accessioned2021-12-16T22:15:46Z-
dc.date.available2021-12-16T22:15:46Z-
dc.date.issued2015-
dc.identifierhttps://doi.org/10.15665/re.v13i2.495-
dc.identifier.issn03036979es
dc.identifier.urihttp://hdl.handle.net/20.500.12494/41759-
dc.description.abstractAim The aim of the present study was to evaluate the clinical and microbiological efficacy of moxifloxacin (MOX) in one-stage scaling and root planing (SRP) in treating generalized aggressive periodontitis (GAgP). Materials and Methods Forty subjects were randomly allocated to two treatment groups. The two treatment groups consisted of SRP combined with systemically admi-nistered MOX at the dosage of 400 mg once daily for 7 days or SRP + placebo once daily for 7 days. Subgingival plaque samples were analysed for cultivable bacteria. Results Both groups resulted in significant reduction of probing depth (PD) and clinical attachment level (CAL) compared with baseline (p < 0.0001), and this difference was maintained at 6 months from baseline in both groups. However, subjects receiving MOX showed the greatest improvements CAL, and PD. Subjects in both groups at 6 months displayed the greatest reduction from baseline in frequency of sites with PD =6 mm (p < 0.001), favouring the MOX group. Adjunctive antibiotic protocol reduced subgingival Aggregatibacter actinomycetemcomitans to undetectable levels, after 3 and 6 months, and there was a significant reduction in the levels of Porphyromonas gingivalis and Tannerella forsythia in the MOX group compared to the placebo group. Conclusions The results from this study suggest that moxifloxacin as and adjunct to one-stage full-mouth SRP leads to a better clinical and microbiological advantages compared to mechanical treatment. © 2014 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.es
dc.description.provenanceMade available in DSpace on 2021-12-16T22:15:46Z (GMT). No. of bitstreams: 0 Previous issue date: 2015en
dc.format.extent168-160es
dc.publisherBlackwell Munksgaardes
dc.relation.ispartofJournal of Clinical Periodontologyes
dc.subjectantiinfective agentes
dc.subjectmoxifloxacines
dc.subjectplaceboes
dc.subjectquinolone derivativees
dc.subjectadultes
dc.subjectAggregatibacter actinomycetemcomitanses
dc.subjectaggressive periodontitises
dc.subjectbacterial loades
dc.subjectBacteroideses
dc.subjectcomparative studyes
dc.subjectcontrolled studyes
dc.subjectdrug effectses
dc.subjectfemalees
dc.subjectfollow upes
dc.subjectGingival Hemorrhagees
dc.subjecthumanes
dc.subjectisolation and purificationes
dc.subjectmalees
dc.subjectmicrobiologyes
dc.subjectmultimodality cancer therapyes
dc.subjectPeriodontal Attachment Losses
dc.subjectperiodontal pocketes
dc.subjectPorphyromonas gingivalises
dc.subjectpreventive dentistryes
dc.subjectprocedureses
dc.subjectrandomized controlled triales
dc.subjecttooth plaquees
dc.subjecttreatment outcomees
dc.subjectyoung adultes
dc.subjectAdultes
dc.subjectAggregatibacter actinomycetemcomitanses
dc.subjectAggressive Periodontitises
dc.subjectAnti-Bacterial Agentses
dc.subjectBacterial Loades
dc.subjectBacteroideses
dc.subjectCombined Modality Therapyes
dc.subjectDental Plaquees
dc.subjectDental Scalinges
dc.subjectFemalees
dc.subjectFluoroquinoloneses
dc.subjectFollow-Up Studieses
dc.subjectGingival Hemorrhagees
dc.subjectHumanses
dc.subjectMalees
dc.subjectPeriodontal Attachment Losses
dc.subjectPeriodontal Pocketes
dc.subjectPlaceboses
dc.subjectPorphyromonas gingivalises
dc.subjectRoot Planinges
dc.subjectTreatment Outcomees
dc.subjectYoung Adultes
dc.titleAdjunctive moxifloxacin in the treatment of generalized aggressive periodontitis patients: clinical and microbiological results of a randomized, triple-blind and placebo-controlled clinical triales
dc.typeArtículo-
dc.creator.mailes
dc.identifier.bibliographicCitationArdila CM,Martelo JF,Boderth G,Ariza AA,Guzmán IC. Adjunctive moxifloxacin in the treatment of generalized aggressive periodontitis patients: clinical and microbiological results of a randomized, triple-blind and placebo-controlled clinical trial. J Clin Periodontol. 2015. 42. (2):p. 160-168. .es
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