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Title: Genomic Epidemiology of Severe Acute Respiratory Syndrome Coronavirus 2, Colombia
Author: Laiton-Donato, Katherine
Villabona-Arenas, Christian J.
Usme-Ciro, Jose A.
Franco-Muñoz, Carlos
Alvarez-Diaz, Diego A.
Villabona-Arenas, Liz S.
Echeverria-Londoño, Susy
Cucunuba, Zulma M.
Franco-Sierra, Nicolas D.
Florez, Astrid C.
Ferro, Carolina
Ajami, Nadim J.
Walteros, Diana M.
Prieto, Franklin
Duran, Carlos A.
Ospina-Martinez, Martha L.
Mercado-Reyes, Marcela
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Issue Date: 16-Nov-2020
Keywords: Coronavirus
Abstract: Coronavirus disease (COVID-19) in Colombia was first diagnosed in a traveler arriving from Italy on February 26, 2020. However, limited data are available on the origins and number of introductions of COVID-19 into the country. We sequenced the causative agent of COVID-19, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), from 43 clinical samples we collected, along with another 79 genome sequences available from Colombia. We investigated the emergence and importation routes for SARSCoV-2 into Colombia by using epidemiologic, historical air travel, and phylogenetic observations. Our study provides evidence of multiple introductions, mostly from Europe, and documents >12 lineages. Phylogenetic findings validate the lineage diversity, support multiple importation events, and demonstrate the evolutionary relationship of epidemiologically linked transmission chains. Our results reconstruct the early evolutionary history of SARS-CoV-2 in Colombia and highlight the advantages of genome sequencing to complement COVID-19 outbreak investigations.
Program: Medicina
Headquarters: Santa Marta
Type: Artículo
Citation: Laiton-Donato, K., Villabona-Arenas, C., Usme-Ciro, J. A., Franco-Muñoz, C., Álvarez-Díaz, D. A., Villabona-Arenas, L....Mercado-Reyes, M. (2020). Genomic Epidemiology of Severe Acute Respiratory Syndrome Coronavirus 2, Colombia. Emerging Infectious Diseases, 26(12), 2854-2862.
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