Please use this identifier to cite or link to this item:Exportar a:
|Title:||Characterization of the venom of C. d. cumanesis of Colombia: Proteomic analysis and antivenomic study|
|Keywords:||crotamine; crotoxin; disintegrin; lectin; serine proteinase; snake venom; reptilian protein; snake venom; venom antiserum; amino acid sequence; Article; Crotalus; Crotalus durissus cumanensis; electrophoresis; electrospray mass spectrometry; nonhuman; oxidation; protein analysis; protein isolation; proteomics; reversed phase high performance liquid chromatography; Western blotting; animal; chemistry; Colombia; Crotalus; immunology; proteomics; Animals; Antivenins; Colombia; Crotalid Venoms; Crotalus; Proteomics; Reptilian Proteins|
|Resume:||The Colombian rattlesnake Crotalus durissus cumanensis is distributed in three geographic zones of the country: the Atlantic Coast, the upper valley of the Magdalena River, and the eastern plains of the Colombian Orinoquía. Its venom induces neurological symptoms, such as eyelid ptosis, myasthenic facies, and paralysis of the respiratory muscles, which can lead to death. Identification and analysis of C. d. cumanensis showed nine groups of proteins responsible for the neurotoxic effect, of which the crotoxin complex was the most abundant (64.71%). Immunorecognition tests of C. d. cumanensis showed that the use of a commercial antivenom manufactured in Mexico resulted in immunoreactivity. © 2018 by the authors.|
|Appears in Collections:||Artículos Científicos|
Files in This Item:
There are no files associated with this item.
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.