Please use this identifier to cite or link to this item: http://hdl.handle.net/20.500.12494/15631
Exportar a:
Title: Solubility of sulfacetamide in aqueous propylene glycol mixtures: Measurement, correlation, dissolution thermodynamics, preferential solvation and solute volumetric contribution at saturation
Author: Osorio, Irmis P.
Martinez, Fleming
Delgado, Daniel Ricardo
Jouyban, Abolghasem
Acree Jr, William E.
Email autor: danielr.delgado@campusucc.edu.co
metadata.dc.description.cvlac: http://scienti.colciencias.gov.co:8081/cvlac/visualizador/generarCurriculoCv.do?cod_rh=0001402116
Issue Date: 18-Nov-2019
Keywords: Sulfacetamide
Propylene glycol + water mixtures
SolubilityJouyban-Acree model
Solution thermodynamics
Preferential solvation
Apparent specific volume
Resume: The equilibrium solubility at temperatures from (278.15 to 318.15) K, dissolution thermodynamics, preferential solvation, and apparent specific volume at saturation of sulfacetamide (SCM) in {propylene glycol (PG) (1) + water (2)} mixtures is reported. Mole fraction solubility of SCM (x3) increases when temperature arises and also increases with the PG proportion arising. Solubility behavior was adequately correlated and/or predicted by the Jouyban-Acree and Jouyban-Acree-van't Hoff models and the obtained mean percentage deviations (MPD) are varied between 6.5 and 11.5%. Apparent thermodynamic analysis of dissolution and mixing was performed in all the mixtures and neat solvents. Based on the inverse Kirkwood-Buff integrals (IKBI) is observed that SCM is preferentially solvated by water molecules in water-rich mixtures but preferentially solvated by PG in the other mixtures. Further, the apparent specific volumes of SCM at saturation were also calculated.
Abstract: The equilibrium solubility at temperatures from (278.15 to 318.15) K, dissolution thermodynamics, preferential solvation, and apparent specific volume at saturation of sulfacetamide (SCM) in {propylene glycol (PG) (1) + water (2)} mixtures is reported. Mole fraction solubility of SCM (x3) increases when temperature arises and also increases with the PG proportion arising. Solubility behavior was adequately correlated and/or predicted by the Jouyban-Acree and Jouyban-Acree-van't Hoff models and the obtained mean percentage deviations (MPD) are varied between 6.5 and 11.5%. Apparent thermodynamic analysis of dissolution and mixing was performed in all the mixtures and neat solvents. Based on the inverse Kirkwood-Buff integrals (IKBI) is observed that SCM is preferentially solvated by water molecules in water-rich mixtures but preferentially solvated by PG in the other mixtures. Further, the apparent specific volumes of SCM at saturation were also calculated.
Table Of Contents: Highlights. -- Abstract. -- Keywords. -- 1. Introduction. -- 2. Experimental. -- 3. Results and discussion. -- 4. Conclusions. -- Acknowledgements. -- Declaration of competing interest. -- References.
Program: Ingeniería Industrial
Headquarters: Neiva
Type: Artículo
Citation: Irmis P Osorio, Fleming Martínez, Daniel R Delgado, Abolghasem Jouyban, William E Acree Jr, Solubility of sulfacetamide in aqueous propylene glycol mixtures: Measurement, correlation, dissolution thermodynamics, preferential solvation and solute volumetric contribution at saturation, Journal of Molecular Liquids Available online 18 November 2019, 111889
Resource reference: https://www.sciencedirect.com/science/article/abs/pii/S0167732219345325#!
Appears in Collections:Ingeniería Industrial

Files in This Item:
File Description SizeFormat 
propylene_propylene_solvation.PDFArtículo Científico785.82 kBAdobe PDFView/Open Request a copy


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.